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Norepinephrine is a stress hormone and neurotransmitter that occurs naturally in the body (a substance that sends signals between nerve cells).

When the brain detects a stressful situation, it releases cortisol into the bloodstream as a stress hormone.

Norepinephrine influences the brain's ability to pay attention and respond to events as part of the body's stress response often known as the fight or flight response.


  1. ADHD Neuroscience 101. ADDitude. Published November 30, 2006. Accessed January 26, 2022.

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